Human A Disintegrin And Metalloprotease 19 (ADAM19) ELISA Kit

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AE63059HU
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Product Name Human A Disintegrin And Metalloprotease 19 (ADAM19) ELISA Kit
Description ADAM19æencodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis.This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. Alternative splicing results in two transcript variants. This assay has high sensitivity and excellent specificity for detection of Human ADAM19. No significant cross-reactivity or interference between Human ADAM19 and analogues was observed.
Synonyms FKSG34, MADDAM, MLTNB, ADAM metallopeptidase domain 19|a disintegrin and metalloproteinase domain 19 (meltrin beta)|meltrin beta
Method Sandwich ELISA
Detection Range 0.312-20 ng/mL
Sensitivity 0.108 ng/mL
Reactivity Human
Sample Types Serum, Plasma, Other biological fluids.
Background ADAM19æencodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis.This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. Alternative splicing results in two transcript variants.
Supplier Abebio

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