| Product Name | Human Adrenomedullin 2 (ADM2) ELISA Kit |
|---|---|
| Description | ADM2 belongs to a family of calcitonin related peptide hormones important for regulating diverse physiologic functions and the chemical composition of fluids and tissues. ADM2 contains a dibasic cleavage site, followed by a 47-amino acid mature peptide hormone sequence and an alpha-amidation donor glycine at the C terminus.Immunohistochemical analysis of several mouse tissues detected Adm2 in pituitary and stomach. PCR analysis of a human gastrointestinal panel detected ADM2 in almost all regions examined. Immunohistochemical staining showed ADM2 in the muscularis mucosae layer of stomach. Western blot analysis of transfected embryonic kidney cells found mature ADM2 secreted into the culture medium; the apparent molecular mass was about 5.0 kD. This assay has high sensitivity and excellent specificity for detection of Human ADM2. No significant cross-reactivity or interference between Human ADM2 and analogues was observed. |
| Synonyms | RP4-579N16.10, AM2, FLJ21135, dJ579N16.4, OTTHUMP00000196596|intermedin |
| Method | Sandwich ELISA |
| Detection Range | 246.9-20000 pg/mL |
| Sensitivity | 91.5 pg/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | ADM2 belongs to a family of calcitonin related peptide hormones important for regulating diverse physiologic functions and the chemical composition of fluids and tissues. ADM2 contains a dibasic cleavage site, followed by a 47-amino acid mature peptide hormone sequence and an alpha-amidation donor glycine at the C terminus.Immunohistochemical analysis of several mouse tissues detected Adm2 in pituitary and stomach. PCR analysis of a human gastrointestinal panel detected ADM2 in almost all regions examined. Immunohistochemical staining showed ADM2 in the muscularis mucosae layer of stomach. Western blot analysis of transfected embryonic kidney cells found mature ADM2 secreted into the culture medium; the apparent molecular mass was about 5.0 kD. |
| Supplier | Abebio |
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