| Product Name | Human Allograft inflammatory factor 1 (AIF1) ELISA Kit |
|---|---|
| Description | Allograft inflammatory factor 1 is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. This assay has high sensitivity and excellent specificity for detection of Human AIF1. No significant cross-reactivity or interference between Human AIF1 and analogues was observed. |
| Synonyms | DADB-70P7.8, AIF-1, IBA1, IRT-1, interferon gamma responsive transcript|ionized calcium-binding adapter molecule |
| Method | Sandwich ELISA |
| Detection Range | 31.25 -2000 pg/mL |
| Sensitivity | 13.7 pg/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
Allograft inflammatory factor 1 is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. |
| Supplier | Abebio |
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