| Product Name | Human Alpha- (1,3)-fucosyltransferase 11 (FUT11) ELISA Kit |
|---|---|
| Description | Fucosyltransferase 11 belongs to the glycosyltransferase 10 family. A fucosyltransferase is an enzyme that transfers an L-fucose sugar from a GDP-fucose (guanosine diphosphate-fucose) donor substrate to an acceptor substrate. The acceptor substrate can be another sugar such as the transfer of a fucose to a core GlcNAc (N-acetylglucosamine) sugar as in the case of N-linked glycosylation, or to a protein, as in the case of O-linked glycosylation produced by O-fucosyltransferase. There are various fucosyltransferases in mammals, the vast majority of which, are located in the Golgi apparatus. The O-fucosyltransferases have recently been shown to localize to the endoplasmic reticulum (ER).Fucosyltransferase activity may be a risk factor for urinary tract infection. This assay has high sensitivity and excellent specificity for detection of Human FUT11. No significant cross-reactivity or interference between Human FUT11 and analogues was observed. |
| Synonyms | MGC119338, MGC119339, MGC33202, |
| Method | Sandwich ELISA |
| Detection Range | 0.156-10 ng/mL |
| Sensitivity | 0.058 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | Fucosyltransferase 11 belongs to the glycosyltransferase 10 family. A fucosyltransferase is an enzyme that transfers an L-fucose sugar from a GDP-fucose (guanosine diphosphate-fucose) donor substrate to an acceptor substrate. The acceptor substrate can be another sugar such as the transfer of a fucose to a core GlcNAc (N-acetylglucosamine) sugar as in the case of N-linked glycosylation, or to a protein, as in the case of O-linked glycosylation produced by O-fucosyltransferase. There are various fucosyltransferases in mammals, the vast majority of which, are located in the Golgi apparatus. The O-fucosyltransferases have recently been shown to localize to the endoplasmic reticulum (ER).Fucosyltransferase activity may be a risk factor for urinary tract infection. |
| Supplier | Abebio |
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