| Product Name | Human Alpha- (1,3)-fucosyltransferase 11 (FUT11) ELISA Kit |
|---|---|
| Description | Human Alpha- (1,3)-fucosyltransferase 11 (FUT11) ELISA Kit has high sensitivity and excellent specificity for detection of Human FUT11. No significant cross-reactivity or interference between Human FUT11 and analogues was observed. Fucosyltransferase 11 belongs to the glycosyltransferase 10 family. A fucosyltransferase is an enzyme that transfers an L-fucose sugar from a GDP-fucose (guanosine diphosphate-fucose) donor substrate to an acceptor substrate. The acceptor substrate can be another sugar such as the transfer of a fucose to a core GlcNAc (N-acetylglucosamine) sugar as in the case of N-linked glycosylation, or to a protein, as in the case of O-linked glycosylation produced by O-fucosyltransferase. There are various fucosyltransferases in mammals, the vast majority of which, are located in the Golgi apparatus. The O-fucosyltransferases have recently been shown to localize to the endoplasmic reticulum (ER).Fucosyltransferase activity may be a risk factor for urinary tract infection. This Human Alpha- (1,3)-fucosyltransferase 11 (FUT11) ELISA Kit employs a two-site sandwich ELISA to quantitate FUT11 in samples. An antibody specific for FUT11 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyFUT11 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for FUT11 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of FUT11 bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | FUT11, MGC119338, MGC119339, MGC33202, |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Human |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Gene Id | 170384 |
| Storage | 2-8°C |
| Background | Fucosyltransferase 11 belongs to the glycosyltransferase 10 family. A fucosyltransferase is an enzyme that transfers an L-fucose sugar from a GDP-fucose (guanosine diphosphate-fucose) donor substrate to an acceptor substrate. The acceptor substrate can be another sugar such as the transfer of a fucose to a core GlcNAc (N-acetylglucosamine) sugar as in the case of N-linked glycosylation, or to a protein, as in the case of O-linked glycosylation produced by O-fucosyltransferase. There are various fucosyltransferases in mammals, the vast majority of which, are located in the Golgi apparatus. The O-fucosyltransferases have recently been shown to localize to the endoplasmic reticulum (ER).Fucosyltransferase activity may be a risk factor for urinary tract infection. |
| Supplier | Abbkine |
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