Human Alpha-fetoprotein Lens culinaris agglutiin 3 (AFP-L3) ELISA Kit
| Product Name | Human Alpha-fetoprotein Lens culinaris agglutiin 3 (AFP-L3) ELISA Kit |
|---|---|
| Description | AFP-L3 is one of AFP fractions which is synthesized by malignant cell and comprise special oligosaccharide.It is a new generation of tumor marker for HCC and yields useful information on HCC for clinical decision making. Reports at home or abroad have showed that if the ratio of AFP-L3 increased over 10%, the risk of catching HCC had increased highly, and non-malignant diseases hardly synthesize this AFP fraction(AFP-L3).AFP-L3 can be detected 9-12 months earlier and shows the remarkable precaution effect to HCC. AFP-L3 is the fucosylated variant of AFP produced specifically by HCC. AFP-L3 bears strong affinity to the sugar chain of Lens culinaris, a type of lentil. AFP-L3 is less sensitive but more specific than AFP, and therefore cannot replace AFP. The value of AFP-L3 lies mainly in distinguishing HCC from other conditions when AFP is elevated. This assay has high sensitivity and excellent specificity for detection of Human AFP-L3. No significant cross-reactivity or interference between Human AFP-L3 and analogues was observed. |
| Method | Sandwich ELISA |
| Detection Range | 0.625-40 ng/mL |
| Sensitivity | 0.244 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | AFP-L3 is one of AFP fractions which is synthesized by malignant cell and comprise special oligosaccharide.It is a new generation of tumor marker for HCC and yields useful information on HCC for clinical decision making. Reports at home or abroad have showed that if the ratio of AFP-L3 increased over 10%, the risk of catching HCC had increased highly, and non-malignant diseases hardly synthesize this AFP fraction(AFP-L3).AFP-L3 can be detected 9-12 months earlier and shows the remarkable precaution effect to HCC. AFP-L3 is the fucosylated variant of AFP produced specifically by HCC. AFP-L3 bears strong affinity to the sugar chain of Lens culinaris, a type of lentil. AFP-L3 is less sensitive but more specific than AFP, and therefore cannot replace AFP. The value of AFP-L3 lies mainly in distinguishing HCC from other conditions when AFP is elevated. |
| Supplier | Abebio |
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