Human Anti-alpha 1 adrenergic receptor IgG antibody (ADRA1-Ab-IgG) ELISA Kit
| Product Name | Human Anti-alpha 1 adrenergic receptor IgG antibody (ADRA1-Ab-IgG) ELISA Kit |
|---|---|
| Description | Human Anti-alpha 1 adrenergic receptor IgG antibody (ADRA1-Ab-IgG) ELISA Kit has high sensitivity and excellent specificity for detection of Human ADRA1-Ab-IgG. No significant cross-reactivity or interference between Human ADRA1-Ab-IgG and analogues was observed. The alpha 1c- Adrenergic Receptor, also known as alpha 1a-adrenoceptor, is activated by epinephrine and norepinephrine. This receptor mediates calcium release upon ligand binding. The alpha 1-c adrenoceptor is one of three subtypes of alpha 1-adrenergic receptor (alpha 1 c/a, alpha 1b, and alpha 1d). The alpha 1c receptor couples to phospholipase C via a GTP-binding protein insensitive to pertussis toxin. Three isoforms are generated by alternative splicing. However, the corresponding isoforms of the protein have similar ligand-binding properties, effector coupling, and tissue distribution. Expression of this receptor has been reported in prostate, liver, kidney, heart, brain, spinal cord, bladder, and various blood vessels. ESTs have been isolated from liver and testis libraries. This Human Anti-alpha 1 adrenergic receptor IgG antibody (ADRA1-Ab-IgG) ELISA Kit employs a two-site sandwich ELISA to quantitate ADRA1-Ab-IgG in samples. An antibody specific for ADRA1-Ab-IgG has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyADRA1-Ab-IgG present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ADRA1-Ab-IgG is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ADRA1-Ab-IgG bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | ADRA1-Ab-IgG |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Human |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Storage | 2-8°C |
| Background | The alpha 1c- Adrenergic Receptor, also known as alpha 1a-adrenoceptor, is activated by epinephrine and norepinephrine. This receptor mediates calcium release upon ligand binding. The alpha 1-c adrenoceptor is one of three subtypes of alpha 1-adrenergic receptor (alpha 1 c/a, alpha 1b, and alpha 1d). The alpha 1c receptor couples to phospholipase C via a GTP-binding protein insensitive to pertussis toxin. Three isoforms are generated by alternative splicing. However, the corresponding isoforms of the protein have similar ligand-binding properties, effector coupling, and tissue distribution. Expression of this receptor has been reported in prostate, liver, kidney, heart, brain, spinal cord, bladder, and various blood vessels. ESTs have been isolated from liver and testis libraries. |
| Supplier | Abbkine |
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