| Product Name | Human Anti-CSFV IgG Antibody (CSFV-Ab-IgG) ELISA Kit |
|---|---|
| Description | Human Anti-CSFV IgG Antibody (CSFV-Ab-IgG) ELISA Kit has high sensitivity and excellent specificity for detection of Human CSFV-Ab-IgG. No significant cross-reactivity or interference between Human CSFV-Ab-IgG and analogues was observed. Classical Swine Fever Virus (CSFV), Bovine Viral Diarrhoea Virus (BVDV), and Border Disease Virus (BDV) are the 3 members of the genus Pestivirus within the family Flaviviridae. CSFV causes serious losses in the pig industry since it is highly contagious and pathogenic, and can cause widespread deaths. Pigs infected with CSFV may shed a high amount of virus before showing clinical signs of the disease. If animals survive an acute or sub-acute infection they develop antibodies or become chronically infected, a situation where pigs excrete the virus intermittently or continuously until death. In pregnant sows, CSFV is able to cross the placenta and infect fetuses. It causes abortions, fetal mummification and stillborns; if the infection occurs mid gestation (~50-70 days of pregnancy), weak or persistently viremic piglets can be born. These persistently infected piglets are able to spread the virus, due to the absence of an immune response. Occasionally pigs may be infected with BVDV or BDV. These infections in pigs are usually mild and self-limiting, but it is important to identify them from the CSFV infection. This Human Anti-CSFV IgG Antibody (CSFV-Ab-IgG) ELISA Kit employs the competitive enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with an antibody specific to CSFV-Ab-IgG. Standards or samples are then added to the appropriate microtiter plate wells with a Horseradish Peroxidase (HRP)-conjugated CSFV-Ab-IgG and incubated. The competitive inhibition reaction is launched between with HRP labeled CSFV-Ab-IgG and unlabeled CSFV-Ab-IgG with the antibody. A substrate solution is added to the wells and the color develops in opposite to the amount of CSFV-Ab-IgG in the sample. The color development is stopped and the intensity of the color is measured. |
| Synonyms | CSFV-Ab-IgG |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Human |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Storage | 2-8°C |
| Background | Classical Swine Fever Virus (CSFV), Bovine Viral Diarrhoea Virus (BVDV), and Border Disease Virus (BDV) are the 3 members of the genus Pestivirus within the family Flaviviridae. CSFV causes serious losses in the pig industry since it is highly contagious and pathogenic, and can cause widespread deaths. Pigs infected with CSFV may shed a high amount of virus before showing clinical signs of the disease. If animals survive an acute or sub-acute infection they develop antibodies or become chronically infected, a situation where pigs excrete the virus intermittently or continuously until death. In pregnant sows, CSFV is able to cross the placenta and infect fetuses. It causes abortions, fetal mummification and stillborns; if the infection occurs mid gestation (~50-70 days of pregnancy), weak or persistently viremic piglets can be born. These persistently infected piglets are able to spread the virus, due to the absence of an immune response. Occasionally pigs may be infected with BVDV or BDV. These infections in pigs are usually mild and self-limiting, but it is important to identify them from the CSFV infection. |
| Supplier | Abbkine |
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