| Product Name | Human Anti-growth hormone antibody (GHAb) ELISA Kit |
|---|---|
| Description | Human Anti-growth hormone antibody (GHAb) ELISA Kit has high sensitivity and excellent specificity for detection of Human GHAb. No significant cross-reactivity or interference between Human GHAb and analogues was observed. Somatotropin is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity.Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. This Human Anti-growth hormone antibody (GHAb) ELISA Kit employs the competitive enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with an antibody specific to GHAb. Standards or samples are then added to the appropriate microtiter plate wells with a Horseradish Peroxidase (HRP)-conjugated GHAb and incubated. The competitive inhibition reaction is launched between with HRP labeled GHAb and unlabeled GHAb with the antibody. A substrate solution is added to the wells and the color develops in opposite to the amount of GHAb in the sample. The color development is stopped and the intensity of the color is measured. |
| Synonyms | GHAb |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Human |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Storage | 2-8°C |
| Background | Somatotropin is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity.Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. |
| Supplier | Abbkine |
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