| Product Name | Human Beta-crosslaps (BCTX) ELISA Kit |
|---|---|
| Description | CrossLaps peptide is a part of the C-telopeptide of the beta 1-chain of type I collagen of bone, is a recently developed biochemical marker of bone turnover.Serum beta-crosslaps are an established laboratory test to investigate bone metabolism. However, lytic conditions may affect the measurement of serum beta-crosslaps. the influence of proteolytic conditions on the serum concentration of beta-crosslaps is not uniform. Leukocyte lysate decreased serum beta-crosslaps while the addition of cathepsin C increased their concentration. Therefore, serum should be separated from the whole blood immediately after coagulation and stored until analysis in a deep freezer. Aliases: B-CTx; Beta CrossLaps; Beta-CTx; C-Telopeptide; C-terminal collagen crosslinks; Carboxy terminal collagen crosslinks; CTx; Soft-CTX. This assay has high sensitivity and excellent specificity for detection of Human BCTX. No significant cross-reactivity or interference between Human BCTX and analogues was observed. |
| Synonyms | b-CTx, bCTXI, bCTX-I, B-Cr, BCL, Type I Collagen C-Telopeptide-Related Fraction |
| Method | Sandwich ELISA |
| Detection Range | 98.77-8000 pg/mL |
| Sensitivity | 36.49 pg/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | CrossLaps peptide is a part of the C-telopeptide of the beta 1-chain of type I collagen of bone, is a recently developed biochemical marker of bone turnover.Serum beta-crosslaps are an established laboratory test to investigate bone metabolism. However, lytic conditions may affect the measurement of serum beta-crosslaps. the influence of proteolytic conditions on the serum concentration of beta-crosslaps is not uniform. Leukocyte lysate decreased serum beta-crosslaps while the addition of cathepsin C increased their concentration. Therefore, serum should be separated from the whole blood immediately after coagulation and stored until analysis in a deep freezer. Aliases: B-CTx; Beta CrossLaps; Beta-CTx; C-Telopeptide; C-terminal collagen crosslinks; Carboxy terminal collagen crosslinks; CTx; Soft-CTX |
| Supplier | Abebio |
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