| Product Name | Human Candida albicans (C.albicans) ELISA Kit |
|---|---|
| Description | Human Candida albicans (C.albicans) ELISA Kit has high sensitivity and excellent specificity for detection of Human C.albicans. No significant cross-reactivity or interference between Human C.albicans and analogues was observed. Candida albicans is a type of yeast that is commonly used as a model organism for biology. It is generally referred to as a dimorphic fungus since it grows both as yeast and filamentous cells. However it has several different morphological phenotypes that are discussed more in detail in the chapter on Morphology. Different morphological forms of Candida albicans: the scale bar is 50 µm. It is a common member of human gut flora and does not seem to proliferate outside mammalian hosts. It is detectable in the gastrointestinal tract and mouth in 40-60% of healthy adults. It is usually a commensal organism, but can become pathogenic in immunocompromised individuals under a variety of conditions. It is one of the few species of the Candida genus that cause the infection candidiasis in humans. Overgrowth of the fungus results in candidiasis (candidosis). Candidiasis is for example often observed in HIV-infected patients. C. albicans is the most common fungal species isolated from biofilms either formed on (permanent) implanted medical devices or on human tissue. C. albicans, together with C. tropicalis, C. parapsilosis and C. glabrata, is responsible for 50–90% of all cases of candidiasis in humans. A mortality rate of 40% has been reported for patients with systemic candidiasis due to C. albicans. Estimates range from 2800 to 11200 deaths caused annually in the USA due to C. albicans causes candidiasis. This Human Candida albicans (C.albicans) ELISA Kit employs a two-site sandwich ELISA to quantitate C.albicans in samples. An antibody specific for C.albicans has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyC.albicans present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for C.albicans is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of C.albicans bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | C.albicans |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Human |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Storage | 2-8°C |
| Background | Candida albicans is a type of yeast that is commonly used as a model organism for biology. It is generally referred to as a dimorphic fungus since it grows both as yeast and filamentous cells. However it has several different morphological phenotypes that are discussed more in detail in the chapter on Morphology. Different morphological forms of Candida albicans: the scale bar is 50 µm. It is a common member of human gut flora and does not seem to proliferate outside mammalian hosts. It is detectable in the gastrointestinal tract and mouth in 40-60% of healthy adults. It is usually a commensal organism, but can become pathogenic in immunocompromised individuals under a variety of conditions. It is one of the few species of the Candida genus that cause the infection candidiasis in humans. Overgrowth of the fungus results in candidiasis (candidosis). Candidiasis is for example often observed in HIV-infected patients. C. albicans is the most common fungal species isolated from biofilms either formed on (permanent) implanted medical devices or on human tissue. C. albicans, together with C. tropicalis, C. parapsilosis and C. glabrata, is responsible for 50–90% of all cases of candidiasis in humans. A mortality rate of 40% has been reported for patients with systemic candidiasis due to C. albicans. Estimates range from 2800 to 11200 deaths caused annually in the USA due to C. albicans causes candidiasis. |
| Supplier | Abbkine |
All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.
