Human Cell division cycle 7-related protein kinase (CDC7) ELISA Kit
| Product Name | Human Cell division cycle 7-related protein kinase (CDC7) ELISA Kit |
|---|---|
| Description | Human Cell division cycle 7-related protein kinase (CDC7) ELISA Kit has high sensitivity and excellent specificity for detection of Human CDC7. No significant cross-reactivity or interference between Human CDC7 and analogues was observed. CDC7 encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of CDC7 product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. This Human Cell division cycle 7-related protein kinase (CDC7) ELISA Kit employs a two-site sandwich ELISA to quantitate CDC7 in samples. An antibody specific for CDC7 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyCDC7 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CDC7 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CDC7 bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | CDC7, CDC7L1, HsCDC7, Hsk1, MGC117361, MGC126237, MGC126238, huCDC7, CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1, cell division cycle 7, cell division cycle 7-like protein 1 |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Human |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Gene Id | 8317 |
| Storage | 2-8°C |
| Background | CDC7 encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of CDC7 product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. |
| Supplier | Abbkine |
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