Human CKLF-like MARVEL transmembrane domain-containing protein 6 (CMTM6) ELISA Kit

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AE61406HU
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Product Name Human CKLF-like MARVEL transmembrane domain-containing protein 6 (CMTM6) ELISA Kit
Description Members of the chemokine-like factor superfamily, including CKLFSF6, share similarity with both the chemokine and the transmembrane 4 superfamilies of signaling molecules.By screening databases for sequences that share homology with chemokine-like factor (CKLF), followed by RT-PCR of a prostate cDNA library, Han et al. (2003) cloned CKLFSF6. The deduced 183-amino acid CKLFSF6 protein has 4 transmembrane segments. It shares about 31% sequence identity with CKLFSF4 . Northern blot analysis detected a transcript of 3.88 kb expressed in leukocytes, placenta, and testis. A smaller transcript was also detected in leukocytes. Han et al. (2003) cloned mouse Cklfsf6, which shares about 88.5% sequence similarity with CKLFSF6. This assay has high sensitivity and excellent specificity for detection of Human CMTM6. No significant cross-reactivity or interference between Human CMTM6 and analogues was observed.
Synonyms CKLFSF6, FLJ20396, PRO2219, chemokine-like factor super family 6|chemokine-like factor superfamily 6
Method Sandwich ELISA
Detection Range 61.7-5000 pg/mL
Sensitivity 2.9 pg/mL
Reactivity Human
Sample Types Serum, Plasma, Other biological fluids.
Background Members of the chemokine-like factor superfamily, including CKLFSF6, share similarity with both the chemokine and the transmembrane 4 superfamilies of signaling molecules.By screening databases for sequences that share homology with chemokine-like factor (CKLF), followed by RT-PCR of a prostate cDNA library, Han et al. (2003) cloned CKLFSF6. The deduced 183-amino acid CKLFSF6 protein has 4 transmembrane segments. It shares about 31% sequence identity with CKLFSF4 . Northern blot analysis detected a transcript of 3.88 kb expressed in leukocytes, placenta, and testis. A smaller transcript was also detected in leukocytes. Han et al. (2003) cloned mouse Cklfsf6, which shares about 88.5% sequence similarity with CKLFSF6.
Supplier Abebio

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