| Product Name | Human Collagen,type V,alpha 1 (COL5A1) ELISA Kit |
|---|---|
| Description | Human Collagen,type V,alpha 1 (COL5A1) ELISA Kit has high sensitivity and excellent specificity for detection of Human COL5A1. No significant cross-reactivity or interference between Human COL5A1 and analogues was observed. Collagen alpha-1(V) chain is alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen.This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. This Human Collagen,type V,alpha 1 (COL5A1) ELISA Kit employs a two-site sandwich ELISA to quantitate COL5A1 in samples. An antibody specific for COL5A1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyCOL5A1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for COL5A1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of COL5A1 bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | COL5A1, RP11-263F14.1, alpha 1 type V collagen |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Human |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Gene Id | 1289 |
| Storage | 2-8°C |
| Background | Collagen alpha-1(V) chain is alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen.This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. |
| Supplier | Abbkine |
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