Human DNA repair protein complementing XP-C cells (XPC) ELISA Kit
| Product Name | Human DNA repair protein complementing XP-C cells (XPC) ELISA Kit |
|---|---|
| Description | Xeroderma pigmentosum, complementation group C, also known as XPC, is a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation.Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. This assay has high sensitivity and excellent specificity for detection of Human XPC. No significant cross-reactivity or interference between Human XPC and analogues was observed. |
| Synonyms | RAD4, XP3, XPCC, xeroderma pigmentosum group C protein |
| Method | Sandwich ELISA |
| Detection Range | 0.312-20 ng/mL |
| Sensitivity | 0.112 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
Xeroderma pigmentosum, complementation group C, also known as XPC, is a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation.Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. |
| Supplier | Abebio |
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