| Product Name | Human Enteropeptidase (PRSS7) ELISA Kit |
|---|---|
| Description | Enteropeptidase is an enzyme involved in human digestion. It is produced by cells in the duodenum wall, and is secreted from duodenum's glands, the crypts of LieberkÙhn, whenever ingested food enters the duodenum from the stomach. Enteropeptidase has the critical job of turning trypsinogen (a zymogen) to trypsin, indirectly activating a number of pancreatic digestive enzymes. Enteropeptidase is a serine protease enzyme (EC 3.4.21.9) which converts inactive trypsinogen into active trypsin by cleavage at the C-terminal end of the sequence. It consists of a disulfide-linked 82_140 kDa heavy chain which anchors enterokinase in the intestinal brush border membrane and a 35_62 kDa light chain which is the catalytic subunit. This assay has high sensitivity and excellent specificity for detection of Human PRSS7. No significant cross-reactivity or interference between Human PRSS7 and analogues was observed. |
| Synonyms | ENTK, MGC133046, enterokinase|enteropeptidase |
| Method | Sandwich ELISA |
| Detection Range | Request Information |
| Sensitivity | Request Information |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
Enteropeptidase is an enzyme involved in human digestion. It is produced by cells in the duodenum wall, and is secreted from duodenum's glands, the crypts of LieberkÙhn, whenever ingested food enters the duodenum from the stomach. Enteropeptidase has the critical job of turning trypsinogen (a zymogen) to trypsin, indirectly activating a number of pancreatic digestive enzymes. Enteropeptidase is a serine protease enzyme (EC 3.4.21.9) which converts inactive trypsinogen into active trypsin by cleavage at the C-terminal end of the sequence. It consists of a disulfide-linked 82_140 kDa heavy chain which anchors enterokinase in the intestinal brush border membrane and a 35_62 kDa light chain which is the catalytic subunit. |
| Supplier | Abebio |
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