Human Epidermal growth factor-like protein 6 (EGFL6) ELISA Kit
| Product Name | Human Epidermal growth factor-like protein 6 (EGFL6) ELISA Kit |
|---|---|
| Description | EGFL6 encodes a member of the epidermal growth factor (EGF) repeat superfamily.The predicted 553-amino acid EGFL6 protein has a putative N-terminal signal peptide, which suggests that it is secreted; an EGF repeat region containing 4 complete EGF-like repeats and 1 partial EGF-like repeat; an integrin association motif (RGD); 2 potential N-glycosylation sites; and a potential tyrosine phosphorylation site. Northern blot analysis of a variety of normal human tissues detected an approximately 2.4-kb EGFL6 transcript only in placenta. Among the cancer tissues tested, EGFL6 expression was found only in meningioma tumors. Screening-by-hybridization analysis of various cDNA libraries indicated EGFL6 expression in lung tumor, fetal lung, fetal skin, fetal umbilical cord, fetal liver/spleen, and placenta, but not in normal adult tissues, including lung. This assay has high sensitivity and excellent specificity for detection of Human EGFL6. No significant cross-reactivity or interference between Human EGFL6 and analogues was observed. |
| Synonyms | DKFZp564P2063, MAEG, W80, EGF repeat-containing protein 6|MAM and EGF domain containing|epidermal growth factor-like protein 6 |
| Method | Sandwich ELISA |
| Detection Range | 93.75-6000 pg/mL |
| Sensitivity | 35.95 pg/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | EGFL6 encodes a member of the epidermal growth factor (EGF) repeat superfamily.The predicted 553-amino acid EGFL6 protein has a putative N-terminal signal peptide, which suggests that it is secreted; an EGF repeat region containing 4 complete EGF-like repeats and 1 partial EGF-like repeat; an integrin association motif (RGD); 2 potential N-glycosylation sites; and a potential tyrosine phosphorylation site. Northern blot analysis of a variety of normal human tissues detected an approximately 2.4-kb EGFL6 transcript only in placenta. Among the cancer tissues tested, EGFL6 expression was found only in meningioma tumors. Screening-by-hybridization analysis of various cDNA libraries indicated EGFL6 expression in lung tumor, fetal lung, fetal skin, fetal umbilical cord, fetal liver/spleen, and placenta, but not in normal adult tissues, including lung. |
| Supplier | Abebio |
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