| Product Name | Human FGF 23 ELISA |
|---|---|
| Description | Fibroblast growth factor 23 is a bone-derived hormone regulating phosphate and vitamin D metabolism. FGF23 is secreted by osteocytes/osteoblasts and works by binding to the klotho–FGF receptor complex. Suppresses proximal tubular phosphate reabsorption by reducing the expression of sodium–phosphate cotransporters, and also inhibits intestinal phosphate absorption by modulating the expression of vitamin D-metabolizing enzymes and reducing 1,25-dihydroxyvitamin D level Excessive and deficient actions of FGF23 cause hypophosphatemic and hyperphosphatemic diseases A key player in mineral and bone disorder in chronic kidney disease (CKD) |
| Detection Range | 2400 - 37.5 pg/ml |
| Sensitivity | 25 pg/ml |
| Sample Types | Plasma |
| Supplier | Biolab Assays |
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