| Product Name | Human Histone H2B type 1-D (HIST1H2BD) ELISA Kit |
|---|---|
| Description | The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Two transcripts that encode the same protein have been identified for this gene, which is found in the large histone gene cluster on chromosome 6p22-p21.3. Albig et al. (1991) identified a gene encoding a member of the H2B class of histones and designated it H2B.1B. Albig and Doenecke (1997) designated this gene H2B/b.By analysis of a YAC contig, Albig et al. (1997) mapped the H2B/b gene to chromosome 6p21.3, within a cluster of 35 histone genes. This assay has high sensitivity and excellent specificity for detection of Human HIST1H2BD. No significant cross-reactivity or interference between Human HIST1H2BD and analogues was observed. |
| Synonyms | H2B.1B, H2B/b, H2BFB, HIRIP2, MGC90432, dJ221C16.6, H2B histone family, member B|OTTHUMP00000016143|histone 1, H2bd |
| Method | Sandwich ELISA |
| Detection Range | 1.23-100 ng/mL |
| Sensitivity | 0.57 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Two transcripts that encode the same protein have been identified for this gene, which is found in the large histone gene cluster on chromosome 6p22-p21.3. Albig et al. (1991) identified a gene encoding a member of the H2B class of histones and designated it H2B.1B. Albig and Doenecke (1997) designated this gene H2B/b.By analysis of a YAC contig, Albig et al. (1997) mapped the H2B/b gene to chromosome 6p21.3, within a cluster of 35 histone genes. |
| Supplier | Abebio |
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