| Product Name | Human Kallikrein-2 (KLK2) ELISA Kit |
|---|---|
| Description | Kallikrein-2 is a protein encoded by the KLK2 gene.The glandular kallikreins are a distinct group of serine proteases with molecular masses of 25,000 to 40,000 and an ability to release vasoactive peptides from kininogen in vitro, although the kininogenase activity of different kallikreins is highly variable. The true physiologic role of specific kallikreins is often unrelated to the kininogenase activity. In the mouse a major site of kallikrein synthesis is the male submaxillary gland. Glandular kallikreins are also synthesized in the pancreas and kidney. The several kallikreins found in this tissue include epidermal growth factor-binding protein (EGF-BP) and the gamma subunit of nerve growth factor (NGFG;), which are responsible for the processing of EGF and NGF , respectively. This assay has high sensitivity and excellent specificity for detection of Human KLK2. No significant cross-reactivity or interference between Human KLK2 and analogues was observed. |
| Synonyms | KLK2A2, MGC12201, hK2, glandular kallikrein 2|kallikrein 2, prostatic |
| Method | Sandwich ELISA |
| Detection Range | 0.156-10 ng/mL |
| Sensitivity | 0.059 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | Kallikrein-2 is a protein encoded by the KLK2 gene.The glandular kallikreins are a distinct group of serine proteases with molecular masses of 25,000 to 40,000 and an ability to release vasoactive peptides from kininogen in vitro, although the kininogenase activity of different kallikreins is highly variable. The true physiologic role of specific kallikreins is often unrelated to the kininogenase activity. In the mouse a major site of kallikrein synthesis is the male submaxillary gland. Glandular kallikreins are also synthesized in the pancreas and kidney. The several kallikreins found in this tissue include epidermal growth factor-binding protein (EGF-BP) and the gamma subunit of nerve growth factor (NGFG;), which are responsible for the processing of EGF and NGF , respectively. |
| Supplier | Abebio |
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