| Product Name | Human Kappa-casein (CSN3) ELISA Kit |
|---|---|
| Description | KCA gene extends over 8,821 nucleotides and consists of 5 exons ranging from 33 to 496 nucleotides separated by introns ranging from 1,146 to 2,942 nucleotides. The human and bovine KCA genes are very similar, with a conserved gene organization and observed identities of 81% and 87% for exons 1 and 2, respectively. The human alpha-S1-casein, beta-casein, and kappa-casein genes are closely linked and arranged in that order. The distance between the alpha-S1 and beta and between alpha-S1 and kappa is approximately 10 and 300 kb, respectively. The beta-casein gene is oriented in the opposite direction to the alpha-S1 and kappa genes. By fluorescence in situ hybridization, the casein gene family was localized to 4q21.1. This assay has high sensitivity and excellent specificity for detection of Human CSN3. No significant cross-reactivity or interference between Human CSN3 and analogues was observed. |
| Synonyms | CSN10, CSNK, KCA, |
| Method | Sandwich ELISA |
| Detection Range | 3.12-200 ng/mL |
| Sensitivity | 1.31 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
KCA gene extends over 8,821 nucleotides and consists of 5 exons ranging from 33 to 496 nucleotides separated by introns ranging from 1,146 to 2,942 nucleotides. The human and bovine KCA genes are very similar, with a conserved gene organization and observed identities of 81% and 87% for exons 1 and 2, respectively. The human alpha-S1-casein, beta-casein, and kappa-casein genes are closely linked and arranged in that order. The distance between the alpha-S1 and beta and between alpha-S1 and kappa is approximately 10 and 300 kb, respectively. The beta-casein gene is oriented in the opposite direction to the alpha-S1 and kappa genes. By fluorescence in situ hybridization, the casein gene family was localized to 4q21.1. |
| Supplier | Abebio |
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