Human Large neutral amino acids transporter small subunit 1 (SLC7A5) ELISA Kit
| Product Name | Human Large neutral amino acids transporter small subunit 1 (SLC7A5) ELISA Kit |
|---|---|
| Description | LAT1 is a heterodimeric membrane transport protein that preferentially transports neutral branched (valine, leucine, isoleucine) and aromatic (tryptophan, tyrosine) amino acids. LAT is highly expressed in brain capillaries (which form the blood brain barrier) relative to other tissues.CD98 is a glycoprotein that comprises the light subunit of the Large neutral Amino acid Transporter (LAT1). Kanai et al. (1998) used expression cloning to isolate a rat cDNA termed LAT1. They showed that LAT1 encoded a protein necessary for system L amino acid transport, thought to be a major route by which cells import large neutral amino acids with branched or aromatic side chains. This assay has high sensitivity and excellent specificity for detection of Human SLC7A5. No significant cross-reactivity or interference between Human SLC7A5 and analogues was observed. |
| Synonyms | 4F2LC, CD98, D16S469E, E16, LAT1, MPE16, hLAT1, 4F2 light chain|CD98 light chain|L-type amino acid transporter 1|integral membrane protein E16|large neutral amino acids transporter 1|large neutral a |
| Method | Sandwich ELISA |
| Detection Range | 0.156-10 ng/mL |
| Sensitivity | 0.058 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
LAT1 is a heterodimeric membrane transport protein that preferentially transports neutral branched (valine, leucine, isoleucine) and aromatic (tryptophan, tyrosine) amino acids. LAT is highly expressed in brain capillaries (which form the blood brain barrier) relative to other tissues.CD98 is a glycoprotein that comprises the light subunit of the Large neutral Amino acid Transporter (LAT1). Kanai et al. (1998) used expression cloning to isolate a rat cDNA termed LAT1. They showed that LAT1 encoded a protein necessary for system L amino acid transport, thought to be a major route by which cells import large neutral amino acids with branched or aromatic side chains. |
| Supplier | Abebio |
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