Human Peptidoglycan recognition protein 1 (PGLYRP1) ELISA Kit
| Product Name | Human Peptidoglycan recognition protein 1 (PGLYRP1) ELISA Kit |
|---|---|
| Description | Innate nonself immune recognition relies on structures common among invading microbes, a process termed pattern recognition. Peptidoglycan is a fundamental component of the bacterial cell wall and is thus a candidate for a pattern recognized by the immune system. The deduced human PGLYRP protein has 196 amino acids. Both the human and mouse PGLYRP proteins share 43% sequence identity with the T. ni PGLYRP protein. Recombinant mouse Pglyrp protein expressed in insect cells possessed an affinity for peptidoglycan. Dot blot analysis of a number of human tissue mRNAs detected strong expression in bone marrow and weak expression in lung, kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, and fetal spleen. This assay has high sensitivity and excellent specificity for detection of Human PGLYRP1. No significant cross-reactivity or interference between Human PGLYRP1 and analogues was observed. |
| Synonyms | MGC126894, MGC126896, PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L, TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein) |
| Method | Sandwich ELISA |
| Detection Range | 15.6-1000 pg/mL |
| Sensitivity | 3.9 pg/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
Innate nonself immune recognition relies on structures common among invading microbes, a process termed pattern recognition. Peptidoglycan is a fundamental component of the bacterial cell wall and is thus a candidate for a pattern recognized by the immune system. The deduced human PGLYRP protein has 196 amino acids. Both the human and mouse PGLYRP proteins share 43% sequence identity with the T. ni PGLYRP protein. Recombinant mouse Pglyrp protein expressed in insect cells possessed an affinity for peptidoglycan. Dot blot analysis of a number of human tissue mRNAs detected strong expression in bone marrow and weak expression in lung, kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, and fetal spleen. |
| Supplier | Abebio |
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