Human Peptidoglycan recognition protein 3 (PGLYRP3) ELISA Kit
| Product Name | Human Peptidoglycan recognition protein 3 (PGLYRP3) ELISA Kit |
|---|---|
| Description | PGLYRP3 contains an N-terminal signal peptide, followed by PGRP domain IV, a transmembrane segment, PGRP domains III and II, a second transmembrane segment, and PGRP domain I at the C terminus. PGRP domain IV at the N terminus and PGRP domain I at the C terminus are extracellular. PGRPI-alpha shares 33%, 43%, and 68% amino acid identity with PGRPL, PGRPS, and PGRPI-beta (PGLYRP4), respectively. PGRP domain IV in PGRPI-alpha is 96% identical to PGRPI domain IV in PGRPI-beta. RNA dot blot analysis detected strong PGRPI-alpha expression only in esophagus. Northern blot analysis detected a 2.8-kb transcript in esophagus and thymus, and PCR detected expression in esophagus, tonsils, and thymus, with much lower expression in stomach, descending colon, rectum, and brain. This assay has high sensitivity and excellent specificity for detection of Human PGLYRP3. No significant cross-reactivity or interference between Human PGLYRP3 and analogues was observed. |
| Synonyms | MGC149197, PGRP-Ialpha, PGRPIA, PGLYRPIalpha|peptidoglycan recognition protein I alpha|peptidoglycan recognition protein-I-alpha |
| Method | Sandwich ELISA |
| Detection Range | 0.312-20 ng/mL |
| Sensitivity | 0.078 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | PGLYRP3 contains an N-terminal signal peptide, followed by PGRP domain IV, a transmembrane segment, PGRP domains III and II, a second transmembrane segment, and PGRP domain I at the C terminus. PGRP domain IV at the N terminus and PGRP domain I at the C terminus are extracellular. PGRPI-alpha shares 33%, 43%, and 68% amino acid identity with PGRPL, PGRPS, and PGRPI-beta (PGLYRP4), respectively. PGRP domain IV in PGRPI-alpha is 96% identical to PGRPI domain IV in PGRPI-beta. RNA dot blot analysis detected strong PGRPI-alpha expression only in esophagus. Northern blot analysis detected a 2.8-kb transcript in esophagus and thymus, and PCR detected expression in esophagus, tonsils, and thymus, with much lower expression in stomach, descending colon, rectum, and brain. |
| Supplier | Abebio |
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