Human Poliovirus receptor-related protein 1 (PVRL1) ELISA Kit
| Product Name | Human Poliovirus receptor-related protein 1 (PVRL1) ELISA Kit |
|---|---|
| Description | PVRL1, or nectin-1, belongs to the nectin subfamily of immunoglobulin-like adhesion molecules that participate in Ca(2+)-independent cell-cell adhesion. Nectins bind to the actin cytoskeleton through the adaptor protein afadin (MLLT4) and are key components of adherens junctions (summary by Barron et al. (2008)). Members of the immunoglobin (Ig) superfamily have been shown to serve as receptors for various viruses. The human poliovirus receptor (PVR) is an integral membrane protein with one V-like extracellular Ig domain, 2 C-like extracellular Ig domains, a transmembrane region, and an intracytoplasmic region. Lopez et al. (1995) isolated a cDNA for a poliovirus receptor related gene, which they symbolized PRR. This assay has high sensitivity and excellent specificity for detection of Human PVRL1. No significant cross-reactivity or interference between Human PVRL1 and analogues was observed. |
| Synonyms | CD111, CLPED1, ED4, HIgR, HVEC, MGC142031, MGC16207, OFC7, PRR, PRR1, PVRR, PVRR1, SK-12, nectin-1, ectodermal dysplasia 4 (Margarita Island type)|herpesvirus Ig-like receptor|nectin 1|poliovirus re |
| Method | Sandwich ELISA |
| Detection Range | 0.156-10 ng/mL |
| Sensitivity | 0.063 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
PVRL1, or nectin-1, belongs to the nectin subfamily of immunoglobulin-like adhesion molecules that participate in Ca(2+)-independent cell-cell adhesion. Nectins bind to the actin cytoskeleton through the adaptor protein afadin (MLLT4) and are key components of adherens junctions (summary by Barron et al. (2008)). Members of the immunoglobin (Ig) superfamily have been shown to serve as receptors for various viruses. The human poliovirus receptor (PVR) is an integral membrane protein with one V-like extracellular Ig domain, 2 C-like extracellular Ig domains, a transmembrane region, and an intracytoplasmic region. Lopez et al. (1995) isolated a cDNA for a poliovirus receptor related gene, which they symbolized PRR. |
| Supplier | Abebio |
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