Human Programmed cell death 6-interacting protein (PDCD6IP) ELISA Kit
| Product Name | Human Programmed cell death 6-interacting protein (PDCD6IP) ELISA Kit |
|---|---|
| Description | Programmed cell death 6-interacting protein is a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization which may be partly responsible for the protection against cell death.Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. This assay has high sensitivity and excellent specificity for detection of Human PDCD6IP. No significant cross-reactivity or interference between Human PDCD6IP and analogues was observed. |
| Synonyms | AIP1, Alix, DRIP4, HP95, MGC17003, ALG-2 interacting protein 1|ALG-2 interacting protein X|apoptosis-linked gene 2-interacting protein X|dopamine receptor interacting protein 4|programmed cell death |
| Method | Sandwich ELISA |
| Detection Range | 0.312-20 ng/mL |
| Sensitivity | 0.115 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
Programmed cell death 6-interacting protein is a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization which may be partly responsible for the protection against cell death.Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Supplier | Abebio |
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