| Product Name | Human Prospero homeobox protein 2 (PROX2) ELISA Kit |
|---|---|
| Description | PROX2 Belongs to the Prospero homeobox family.Contains 1 Prospero-type homeobox DNA-binding domain.Transcription regulator. Does not seem to be essential for embryonic development and postnatal survival. The prospero domain coincides with a domain in a Drosophila gene that is expressed in Drosophila central nervous system and in the developing lens-secreting cone cells of the eye. Exon 1 of the human sequence showed no clear similarity to the 3 alternatively spliced variants of chicken PROX1 cDNA. Human PROX1 exon 1 was found to contain repetitive sequences. Analysis of mRNA revealed that Prox mRNA was present in many different human tissues and that lens demonstrated the highest level. In all tissues but lens, PROX1 cDNA hybridized to a single band of 8 kb. This assay has high sensitivity and excellent specificity for detection of Human PROX2. No significant cross-reactivity or interference between Human PROX2 and analogues was observed. |
| Synonyms | FLJ36749, |
| Method | Sandwich ELISA |
| Detection Range | 25-1600 pg/mL |
| Sensitivity | 6.25 pg/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
PROX2 Belongs to the Prospero homeobox family.Contains 1 Prospero-type homeobox DNA-binding domain.Transcription regulator. Does not seem to be essential for embryonic development and postnatal survival. The prospero domain coincides with a domain in a Drosophila gene that is expressed in Drosophila central nervous system and in the developing lens-secreting cone cells of the eye. Exon 1 of the human sequence showed no clear similarity to the 3 alternatively spliced variants of chicken PROX1 cDNA. Human PROX1 exon 1 was found to contain repetitive sequences. Analysis of mRNA revealed that Prox mRNA was present in many different human tissues and that lens demonstrated the highest level. In all tissues but lens, PROX1 cDNA hybridized to a single band of 8 kb. |
| Supplier | Abebio |
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