| Product Name | Human Protein Wnt-2b (WNT2B) ELISA Kit |
|---|---|
| Description | WNT2B encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis. This gene produces two alternative transcript variants.WNT13 encodes a 372-amino acid polypeptide including a putative secretory signal peptide. Northern blot analysis revealed that WNT13 was expressed as a 2.5-kb mRNA in fetal brain, lung, and kidney. Unlike most other WNTs, which tend to have restricted expression in adult tissues, its transcript was found in a wide variety of adult tissues. This assay has high sensitivity and excellent specificity for detection of Human WNT2B. No significant cross-reactivity or interference between Human WNT2B and analogues was observed. |
| Synonyms | WNT13, XWNT2, XWNT2, Xenopus, homolog of|wingless-type MMTV integration site family, member 13 |
| Method | Sandwich ELISA |
| Detection Range | 0.156-10 ng/mL |
| Sensitivity | 0.059 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | WNT2B encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis. This gene produces two alternative transcript variants.WNT13 encodes a 372-amino acid polypeptide including a putative secretory signal peptide. Northern blot analysis revealed that WNT13 was expressed as a 2.5-kb mRNA in fetal brain, lung, and kidney. Unlike most other WNTs, which tend to have restricted expression in adult tissues, its transcript was found in a wide variety of adult tissues. |
| Supplier | Abebio |
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