Human Pulmonary surfactant-associated protein C (SP-C) ELISA Kit
| Product Name | Human Pulmonary surfactant-associated protein C (SP-C) ELISA Kit |
|---|---|
| Description | SP-C is a fragment of a much larger precursor protein of 21 kD. The precursor contains an exceedingly hydrophobic region of 34 amino acids that comprises most of the mature SP C, and a unique poly-valine domain.Pulmonary surfactant-associated protein C is a membrane protein which manufactures surfactant.Humans and animals born lacking SP-C tend to develop progressive interstitial pneumonitis.The SFTPC gene encodes pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. It is produced exclusively by type II alveolar epithelial cells in the lung. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. This assay has high sensitivity and excellent specificity for detection of Human SFTPC. No significant cross-reactivity or interference between Human SFTPC and analogues was observed. |
| Synonyms | PSP-C, SFTP2, SMDP2, SP-C, pulmonary surfactant apoprotein-2 SP-C|surfactant, pulmonary-associated protein C |
| Method | Sandwich ELISA |
| Detection Range | 0.312-20 ng/mL |
| Sensitivity | 0.126 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | SP-C is a fragment of a much larger precursor protein of 21 kD. The precursor contains an exceedingly hydrophobic region of 34 amino acids that comprises most of the mature SP C, and a unique poly-valine domain.Pulmonary surfactant-associated protein C is a membrane protein which manufactures surfactant.Humans and animals born lacking SP-C tend to develop progressive interstitial pneumonitis.The SFTPC gene encodes pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. It is produced exclusively by type II alveolar epithelial cells in the lung. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. |
| Supplier | Abebio |
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