Human Putative ATP-binding cassette sub-family C member 13 (ABCC13) ELISA Kit

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AE23125HU
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Product Name Human Putative ATP-binding cassette sub-family C member 13 (ABCC13) ELISA Kit
Description Putative ATP-binding cassette transporter sub-family C member 13 is a member of the superfamily of genes encoding ATP-binding cassette (ABC) transporters. This family member is part of the MRP subfamily, which is involved in multi-drug resistance, but the human locus is now thought to be a pseudogene incapable of encoding a functional ABC protein. Alternative splicing results in multiple transcript variants; however, not all variants have been fully described. Highest expression in fetal liver and fetal spleen. In the adult, highest levels are found in the colon ascending and transverse. Also expressed in brain, placenta, lung, liver, pancreas and ovary. In bone marrow cells, levels are several fold higher than in peripheral blood leukocytes. This assay has high sensitivity and excellent specificity for detection of Human ABCC13. No significant cross-reactivity or interference between Human ABCC13 and analogues was observed.
Synonyms C21orf73, PRED6, ATP-binding cassette protein C13
Method Sandwich ELISA
Detection Range 0.156-10 ng/mL
Sensitivity 0.057 ng/mL
Reactivity Human
Sample Types Serum, Plasma, Other biological fluids.
Background Putative ATP-binding cassette transporter sub-family C member 13 is a member of the superfamily of genes encoding ATP-binding cassette (ABC) transporters. This family member is part of the MRP subfamily, which is involved in multi-drug resistance, but the human locus is now thought to be a pseudogene incapable of encoding a functional ABC protein. Alternative splicing results in multiple transcript variants; however, not all variants have been fully described.
Highest expression in fetal liver and fetal spleen. In the adult, highest levels are found in the colon ascending and transverse. Also expressed in brain, placenta, lung, liver, pancreas and ovary. In bone marrow cells, levels are several fold higher than in peripheral blood leukocytes.
Supplier Abebio

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