Human Receptor I for the Fc region of immunoglobulin A (FcARI) ELISA Kit
| Product Name | Human Receptor I for the Fc region of immunoglobulin A (FcARI) ELISA Kit |
|---|---|
| Description | Only one Fc receptor belongs to the Fc alpha R subgroup, which is called Fc alpha RI (or CD89). Fc alpha RI is found on the surface of neutrophils, eosinophils, monocytes, some macrophages (including Kupffer cells), and some dendritic cells. It is composed of two extracellular Ig-like domains, and is a member of both the immunoglobulin superfamily and the multi-chain immune recognition receptor (MIRR) family. It signals by associating with two FcR gamma_signaling chains.Another receptor can also bind IgA, although it has higher affinity for another antibody called IgM. This receptor is called the Fc-alpha/mu receptor (Fc alpha/mu R) and is a type I transmembrane protein. With one Ig-like domain in its extracellular portion, this Fc receptor is also a member of the immunoglobulin superfamily. This assay has high sensitivity and excellent specificity for detection of Human FcARI. No significant cross-reactivity or interference between Human FcARI and analogues was observed. |
| Synonyms | CD89, FcaR, Receptor I For The Fc Region Of Immunoglobulin A |
| Method | Sandwich ELISA |
| Detection Range | 0.78-50 ng/mL |
| Sensitivity | 0.37 ng/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | Only one Fc receptor belongs to the Fc alpha R subgroup, which is called Fc alpha RI (or CD89). Fc alpha RI is found on the surface of neutrophils, eosinophils, monocytes, some macrophages (including Kupffer cells), and some dendritic cells. It is composed of two extracellular Ig-like domains, and is a member of both the immunoglobulin superfamily and the multi-chain immune recognition receptor (MIRR) family. It signals by associating with two FcR gamma_signaling chains.Another receptor can also bind IgA, although it has higher affinity for another antibody called IgM. This receptor is called the Fc-alpha/mu receptor (Fc alpha/mu R) and is a type I transmembrane protein. With one Ig-like domain in its extracellular portion, this Fc receptor is also a member of the immunoglobulin superfamily. |
| Supplier | Abebio |
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