Human Serine/threonine-protein kinase TNNI3K (TNNI3K) ELISA Kit
| Product Name | Human Serine/threonine-protein kinase TNNI3K (TNNI3K) ELISA Kit |
|---|---|
| Description | TNNI3K is a new cardiac-specific MAP kinase whose gene is localized to 1p31.1 and that belongs to a tyrosine kinase-like branch in the kinase tree of the human genome.TNNI3K promoted the differentiation process, judging from the increasing beating mass and increased number of a-actinin-positive cells. TNNI3K improved cardiac function by enhancing beating frequency and increasing the contractile force and epinephrine response of spontaneous action potentials without an increase of the single-cell size. TNNI3K suppressed phosphorylation of cardiac troponin I, annexin-V+ cells, Bax protein, and p38/JNK-mediated apoptosis.TNNI3K promotes cardiomyogenesis, enhances cardiac performance, and protects the myocardium from ischemic injury by suppressing p38/JNK-mediated apoptosis. This assay has high sensitivity and excellent specificity for detection of Human TNNI3K. No significant cross-reactivity or interference between Human TNNI3K and analogues was observed. |
| Synonyms | CARK, MGC142099, MGC33828, cardiac ankyrin repeat kinase |
| Method | Sandwich ELISA |
| Detection Range | Request Information |
| Sensitivity | Request Information |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | TNNI3K is a new cardiac-specific MAP kinase whose gene is localized to 1p31.1 and that belongs to a tyrosine kinase-like branch in the kinase tree of the human genome.TNNI3K promoted the differentiation process, judging from the increasing beating mass and increased number of a-actinin-positive cells. TNNI3K improved cardiac function by enhancing beating frequency and increasing the contractile force and epinephrine response of spontaneous action potentials without an increase of the single-cell size. TNNI3K suppressed phosphorylation of cardiac troponin I, annexin-V+ cells, Bax protein, and p38/JNK-mediated apoptosis.TNNI3K promotes cardiomyogenesis, enhances cardiac performance, and protects the myocardium from ischemic injury by suppressing p38/JNK-mediated apoptosis. |
| Supplier | Abebio |
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