Product Name | Human Testican-1 (SPOCK1) ELISA Kit |
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Description | TIC1 encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition.The SPOCK cDNA encodes a deduced 439-amino acid protein with a predicted N-terminal signal sequence and 2 consensus glycosaminoglycan attachment sites. SPOCK, which contains osteonectin-like domains, a Kazal-like sequence, and a cys-trp-cys-val (CWCV) domain, is related to protein families that are involved in adhesion, migration, and cell proliferation.In situ hybridization showed that mouse Spock1 is located predominantly in a subpopulation of pyramidal neurons in the CA3 area of the hippocampus. This assay has high sensitivity and excellent specificity for detection of Human SPOCK1. No significant cross-reactivity or interference between Human SPOCK1 and analogues was observed. |
Synonyms | FLJ37170, SPOCK, TESTICAN, TIC1, OTTHUMP00000159433|sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1|testican-1 |
Method | Sandwich ELISA |
Detection Range | Request Information |
Sensitivity | Request Information |
Reactivity | Human |
Sample Types | Serum, Plasma, Other biological fluids. |
Background | TIC1 encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition.The SPOCK cDNA encodes a deduced 439-amino acid protein with a predicted N-terminal signal sequence and 2 consensus glycosaminoglycan attachment sites. SPOCK, which contains osteonectin-like domains, a Kazal-like sequence, and a cys-trp-cys-val (CWCV) domain, is related to protein families that are involved in adhesion, migration, and cell proliferation.In situ hybridization showed that mouse Spock1 is located predominantly in a subpopulation of pyramidal neurons in the CA3 area of the hippocampus. |
Supplier | Abebio |
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