| Product Name | Human Vitamin K1 (VK1) ELISA Kit |
|---|---|
| Description | Phylloquinone is a polycyclic aromatic ketone, based on 2-methyl-1,4-naphthoquinone, with a 3-phytyl substituent.It is a fat-soluble vitamin that is stable to air and moisture but decomposes in sunlight. It is found naturally in a wide variety of green plants.It is often called vitamin K1 or phytonadione. Sometimes a distinction is made with phylloquinone considered natural and phytonadione considered synthetic. A stereoisomer of phylloquinone is called vitamin k1 .Its best known mechanism of action is as a cofactor in the formation of coagulation factors II (prothrombin), VII, IX and X by the liver. Vitamin K1 is commonly used to treat warfarin toxicity, and an antidote for coumatetralyl. It is also required for the formation of anticoagulant factors protein C and S. Vitamin K is also required bone protein formation. This assay has high sensitivity and excellent specificity for detection of Human VK1. No significant cross-reactivity or interference between Human VK1 and analogues was observed. |
| Synonyms | Phylloquinone, Phytonadione, Phytomenadione |
| Method | Sandwich ELISA |
| Detection Range | 123.5-10000 pg/mL |
| Sensitivity | 49.3 pg/mL |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
Phylloquinone is a polycyclic aromatic ketone, based on 2-methyl-1,4-naphthoquinone, with a 3-phytyl substituent.It is a fat-soluble vitamin that is stable to air and moisture but decomposes in sunlight. It is found naturally in a wide variety of green plants.It is often called vitamin K1 or phytonadione. Sometimes a distinction is made with phylloquinone considered natural and phytonadione considered synthetic. A stereoisomer of phylloquinone is called vitamin k1 .Its best known mechanism of action is as a cofactor in the formation of coagulation factors II (prothrombin), VII, IX and X by the liver. Vitamin K1 is commonly used to treat warfarin toxicity, and an antidote for coumatetralyl. It is also required for the formation of anticoagulant factors protein C and S. Vitamin K is also required bone protein formation. |
| Supplier | Abebio |
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