| Product Name | Ifnar1, 27-429aa, Mouse, Baculovirus |
|---|---|
| Description | Ifnar1, also known as Interferon alpha/beta receptor 1, is a member of the class II cytokine receptor family of proteins. This protein forms one of the two chains of a receptor for interferons alpha and beta. It binds and activate of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. Recombinant mouse Ifnar1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms | Interferon alpha/beta receptor 1, Ifnar1, CD118, Ifar, Ifnar, Ifrc, Infar |
| Host | Virus |
| Molecular Weight |
37.7kDa (329aa) 40-57kDa (SDS-PAGE under reducing conditions) |
| Amino Acid Sequence | ENLKPPENID VYIIDDNYTL KWSSHGESMG SVTFSAEYRT KDEAKWLKVP ECQHTTTTKC EFSLLDTNVY IKTQFRVRAE EGNSTSSWNE VDPFIPFYTA HMSPPEVRLE AEDKAILVHI SPPGQDGNMW ALEKPSFSYT IRIWQKSSSD KKTINSTYYV EKIPELLPET TYCLEVKAIH PSLKKHSNYS TVQCISTTVA NKMPVPGNLQ VDAQGKSYVL KWDYIASADV LFRAQWLPGY SKSSSGSRSD KWKPIPTCAN VQTTHCVFSQ DTVYTGTFFL HVQASEGNHT SFWSEEKFID SQKHILPPPP VITVTAMSDT LLVYVNCQDS TCDGLNYEII FWENTSNTKI SMEKDGPEFT LKNLQPLTVY CVQARVLFRA LLNKTSNFSE KLCEKTRPGS FSTLEHHHHH H |
| Tag | His-tag |
| Reactivity | Mouse |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Concentration | 0.5mg/ml (determined by Absorbance at 280nm) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Langer JA., et al. (2004) Cytokine Growth Factor Rev. 15:33-48. Yan H., et al. (1996) EMBO J. 15:1064-1074. |
| Background | Ifnar1, also known as Interferon alpha/beta receptor 1, is a member of the class II cytokine receptor family of proteins. This protein forms one of the two chains of a receptor for interferons alpha and beta. It binds and activate of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. Recombinant mouse Ifnar1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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