| Product Name | IFNL1 Antibody, Biotin conjugated |
|---|---|
| Description | Rabbit polyclonal antibody against IFNL1 conjugated to Biotin |
| Synonyms | IFNL1 antibody; IL29 antibody; ZCYTO21Interferon lambda-1 antibody; IFN-lambda-1 antibody; Cytokine Zcyto21 antibody; Interleukin-29 antibody; IL-29 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Biotin |
| Immunogen | Recombinant human Interleukin-29 protein (21-200AA) |
| Isotype | IgG |
| Target | IFNL1 |
| Reactivity | Human |
| Applications | ELISA |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | Q8IU54 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression. |
| Supplier | Cusabio |
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