| Product Name | IL21R Monoclonal Antibody |
|---|---|
| Description | IL21R,a receptor for interleukin-21,belongs to the type I cytokine receptor family. IL21R has been shown to form a heterodimeric receptor complex with the common gamma-chain,a receptor subunit also shared by the receptors for interleukin 2,4,7,9,and 15. This receptor transduces the growth promoting signal of IL21,and is important for the proliferation and differentiation of T cells,B cells,and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules,including JAK1,JAK3,STAT1,and STAT3. |
| Synonyms | CD360,IL 21 receptor,IL 21R,IL21R,interleukin 21 receptor,NILR,Novel interleukin receptor |
| Host | Mouse |
| Clone | 1D1C2 |
| Immunogen | Fusion Protein of IL21R |
| Isotype | IgG2b |
| Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | Q9HBE5 |
| Background | IL21R,a receptor for interleukin-21,belongs to the type I cytokine receptor family. IL21R has been shown to form a heterodimeric receptor complex with the common gamma-chain,a receptor subunit also shared by the receptors for interleukin 2,4,7,9,and 15. This receptor transduces the growth promoting signal of IL21,and is important for the proliferation and differentiation of T cells,B cells,and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules,including JAK1,JAK3,STAT1,and STAT3. |
| Supplier | Elabscience |
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