| Product Name | Integrin alpha-3 Monoclonal Antibody |
|---|---|
| Description | ITGA3,also named as MSK18,CD49c,GAPB3 and FRP-2,belongs to the integrin alpha chain family. It is a receptor for fibronectin,laminin,collagen,epiligrin,thrombospondin and CSPG4. ITGA3 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. ITGA3 is highly concentrated in epithelial cells where it strongly adheres to Laminin-5 and Laminin-5 induced rapid adhesion can be blocked by antibodies against the alpha-3 integrin subunit. It can be cleaved into heavy chain(840aa) and light chain(176aa). This antibody can recognize the heavy chain. |
| Synonyms | CD49C,FLJ34631,FLJ34704,FRP 2,Galactoprotein B3,GAP B3,GAPB3,Integrin alpha 3,ITGA3,MSK18,VCA 2,VL3A,VLA 3 subunit alpha,VLA3a |
| Host | Mouse |
| Clone | 1269 |
| Immunogen | Fusion protein of Integrin alpha-3 |
| Isotype | IgG2a |
| Reactivity | Human |
| Applications | ELISA, IF, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | P26006 |
| Background | ITGA3,also named as MSK18,CD49c,GAPB3 and FRP-2,belongs to the integrin alpha chain family. It is a receptor for fibronectin,laminin,collagen,epiligrin,thrombospondin and CSPG4. ITGA3 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. ITGA3 is highly concentrated in epithelial cells where it strongly adheres to Laminin-5 and Laminin-5 induced rapid adhesion can be blocked by antibodies against the alpha-3 integrin subunit. It can be cleaved into heavy chain(840aa) and light chain(176aa). This antibody can recognize the heavy chain. |
| Supplier | Elabscience |
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