| Product Name | Interleukin-1 alpha, 115-270aa, Rat |
|---|---|
| Description | IL1A also known as interleukin-1 alpha. IL1A belongs to the interleukin 1 cytokine family. IL1A is part of Interleukin-1. IL1 stimulates thymocyte proliferation by inducing IL2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL1 proteins are involved in the inflammatory response, especially IL1A is an early and important mediator of inflammation after injury. Recombinant rat IL1A, fused to His-tag at N-terminus was expressed in E.coli and purified by using conventional chromatography techniques. |
| Synonyms | IL-1 alpha, Il1a |
| Host | E. coli |
| Molecular Weight |
55.8kDa (512aa) 50-70kDa (SDS-PAGE under reducing conditions) |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSSAPHSFQ NNLRYKLIRI VKQEFIMNDS LNQNIYVDMD RIHLKAASLN DLQLEVKFDM YAYSSGGDDS KYPVTLKVSN TQLFVSAQGE DKPVLLKEIP ETPKLITGSE TDLIFFWEKI NSKNYFTSAA FPELLIATKE QSQVHLARGL PSMIDFQIS |
| Tag | His-tag |
| Reactivity | Rat |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Concentration | 1mg/ml (determined by Absorbance at 280nm) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Brough D., et al. (2015) IUBMB Life. doi: 10.1002 Hermann E., et al. (1985) Z Rheumatol. 44(5): 207-12. |
| Background | IL1A also known as interleukin-1 alpha. IL1A belongs to the interleukin 1 cytokine family. IL1A is part of Interleukin-1. IL1 stimulates thymocyte proliferation by inducing IL2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL1 proteins are involved in the inflammatory response, especially IL1A is an early and important mediator of inflammation after injury. Recombinant rat IL1A, fused to His-tag at N-terminus was expressed in E.coli and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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