| Product Name | iPLA2_ Polyclonal Antibody |
|---|---|
| Description | This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. Mutations in this gene have been associated with mitochondrial myopathy with lactic acidosis. Multiple transcript variants encoding different isoforms have been found for this gene.PNPLA8 (Patatin Like Phospholipase Domain Containing 8) is a Protein Coding gene. Diseases associated with PNPLA8 include Mitochondrial Myopathy With Lactic Acidosis and Weaver Syndrome. Among its related pathways are Acyl chain remodelling of PE and Eicosanoid Synthesis. GO annotations related to this gene include binding and calcium-independent phospholipase A2 activity. An important paralog of this gene is PLA2G6. |
| Synonyms | PNPLA8, IPLA22, IPLA2G, BM-043, Calcium-independent phospholipase A2-gamma, Intracellular membrane-associated calcium-independent phospholipase A2 gamma, iPLA2-gamma, PNPLA-gamma, Patatin-like phospholipase domain-containing protein 8, iPLA |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from the C-terminal region of human iPLA2_ |
| Isotype | IgG |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB |
| Form | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Uniprot | Q9NP80 |
| Background | This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. Mutations in this gene have been associated with mitochondrial myopathy with lactic acidosis. Multiple transcript variants encoding different isoforms have been found for this gene.PNPLA8 (Patatin Like Phospholipase Domain Containing 8) is a Protein Coding gene. Diseases associated with PNPLA8 include Mitochondrial Myopathy With Lactic Acidosis and Weaver Syndrome. Among its related pathways are Acyl chain remodelling of PE and Eicosanoid Synthesis. GO annotations related to this gene include binding and calcium-independent phospholipase A2 activity. An important paralog of this gene is PLA2G6. |
| Supplier | Elabscience |
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