| Product Name | ITGAL Monoclonal Antibody,PE Conjugated |
|---|---|
| Description | Mouse monoclonal antibody against ITGAL onjugated to PE |
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Isotype | IgG1 |
| Target | ITGAL |
| Reactivity | Human |
| Applications | ELISA, FC, IF |
| Form | liquid |
| Diluent Buffer | Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA |
| Uniprot | P20701 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
4A122 reacts with CD11a, a 180 kDa molecule. CD11a is the a chain of the leukocyte function associated antigen-1 (LFA-1a), and is expressed on all leukocytes including T and B cells, monocytes, and granulocytes, but is absent on non-hematopoietic tissue and human platelets. CD11/CD18 (LFA-1), a member of the integrin subfamily, is a leukocyte adhesion receptor that is essential for cell-to-cell contact, such as lymphocyte adhesion, NK and T-cell cytolysis, and T-cell proliferation. CD11/CD18 is also involved in the interaction of leucocytes with endothelium *CD11a antibody has been used to reduces graft failure for bone marrow grafts in immunodeficient children. This clone is cross reactive with non-human primate. 1. Schlossman. S et al. (1995) Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York. 2. Lub M et al. (1995) Immunol. Today 16:479. 3. Sanchez-Mateos P et al. (1996) Cancer Biol. 7:99. |
| Supplier | Cusabio |
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