| Product Name | Kininogen 1 Monoclonal Antibody |
|---|---|
| Description | Kininogens are inhibitors of thiol proteases. Kininogen 1 plays important role in Kinin-kallikrein system. This gene is translated into High-molecular weight kininogen (HMWK) and low-molecular weight kininogen (LMWK) after alternative splicing. HMWK is produced by the liver together with prekallikrein. It acts mainly as a cofactor on coagulation and inflammation,and has no intrinsic catalytic activity. LMWK is produced locally by numerous tissues,and secreted together with tissue kallikrein. |
| Synonyms | BDK,Fitzgerald factor,HMWK,Ile Ser Bradykinin Bradykinin,Kallidin I Lysyl bradykinin,kininogen 1,KNG,KNG1 |
| Host | Mouse |
| Clone | 834 |
| Immunogen | Fusion protein of Kininogen 1 |
| Isotype | IgG1 |
| Reactivity | Human |
| Applications | ELISA, IF, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | P01042 |
| Background | Kininogens are inhibitors of thiol proteases. Kininogen 1 plays important role in Kinin-kallikrein system. This gene is translated into High-molecular weight kininogen (HMWK) and low-molecular weight kininogen (LMWK) after alternative splicing. HMWK is produced by the liver together with prekallikrein. It acts mainly as a cofactor on coagulation and inflammation,and has no intrinsic catalytic activity. LMWK is produced locally by numerous tissues,and secreted together with tissue kallikrein. |
| Supplier | Elabscience |
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