| Product Name | Kisspeptin 10 (rat, mouse) |
|---|---|
| Description | Kisspeptin-10 is the endogenous ligand for the rodent kisspeptin receptor (KISS1, GPR54) and is the minimal sequence of metastin (45-54) which activates GPR54 signaling. Kisspeptin has recently emerged as a key regulator of the mammalian reproductive axis while stimulation of GPR54 can also up-regulate proapoptotic genes which have tumour suppressor properties, inhibiting metastasis and invasion in mouse melanomas |
| Synonyms | metastin (45-54), 478507-53-8, GPR54, H-YNWNSFGLRY-NH2, KISS1, Kisspeptin 10 (rat, Kisspeptin-10, NR-060, NR060, YNWNSFGLRY, kisspeptin receptor, metastasis, mouse) |
| Molecular Weight | 1318.5 Da |
| Target | Kisspeptin receptors |
| Amino Acid Sequence | H-YNWNSFGLRY-NH2 |
| Form | Freeze dried solid |
| Purity | >95% by HPLC |
| Cas Number | 478507-53-8 |
| Storage | Store dry, frozen and desiccated |
| Notes | Modifications: C terminal amide |
| References |
Stafford et al (2002) Identification and characterization of mouse metastasis-suppressor KiSS1 and its G-protein-coupled receptor. Cancer Res. 62 5399 PMID: 12359743Navarro et al (2004) Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide. Endocrinology 145 4565 PMID: 15242985Clarke et al (2015) Comprehensive Review on Kisspeptin and Its Role in Reproductive Disorders. Endocrinology and metabolism (Seoul, Korea) 30(2) 124 PMID: 26194072 Related areas All peptides >All kisspeptin receptor modulators >All endocrinology research categories >All cancer research categories > |
| Supplier | Isca Biochemicals Limited |
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