| Product Name | LAIR-1 (Extracellular domain ; 22-125aa, human), Recombinant |
|---|---|
| Description | LAIR-1 is a glycoprotein(~32kDa) expressed on the surface of the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR-1 functions as an inhibitory receptor in NK cells, T cells and B cells. Lair-1 consists of a leader sequence, extracellular domain, transmembrane domain, cytoplasmic region. The extracellular domain of LAIR-1( 22-125aa) was overexpressed in E.coli, and purified by using conventional chromatography techniques. |
| Synonyms | Lair1, LAIR-1 (Extracellular domain), LAIR-1, mLAIR1, CD305 antigen, Leukocyte-associated immunoglobulin-like receptor 1, Leukocyte-associated immunoglobulin-like receptor 1 isoform a 5133400O11Rik, CD305, D7Bwg0421e, LAIR 1, LAIR1 protein, Leukocyte associated Ig like receptor 1, Leukocyte associated immunoglobulin like receptor 1, |
| Host | E. coli |
| Molecular Weight | 22.2kDa (308aa), confirmed by MALDI-TOF. |
| Amino Acid Sequence | MQEEDLPRPS ISAEPGTVIP LGSHVTFVCR GPVGVQTFRL ERESRSTYND TEDVSQASPS ESEARFRIDS VSEGNAGPYR CIYYKPPKWS EQSDYLELLV KETSG |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20 mM Tris-HCl buffer (pH7.5) . |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Sathish JG., et al. (2001) J Immunol. 166(3):1763-70. Meyaard L., et al. (1999) J. Immunol. 162, 5800-4. |
| Background | LAIR-1 is a glycoprotein(~32kDa) expressed on the surface of the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR-1 functions as an inhibitory receptor in NK cells, T cells and B cells. Lair-1 consists of a leader sequence, extracellular domain, transmembrane domain, cytoplasmic region. The extracellular domain of LAIR-1( 22-125aa) was overexpressed in E.coli, and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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