| Product Name | LAMP3, 28-381aa, Human, Baculovirus |
|---|---|
| Description | LAMP3, also known as lysosome-associated membrane glycoprotein 3, is a member of the lysosome-associated membrane protein family. LAMP3 and CD68 share very similar predicted structure. It may play a role in dendritic cell function and in adaptive immunity. Overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces. Recombinant human LAMP3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms | LAMP3, CD208, DC LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403 |
| Host | Virus |
| Molecular Weight |
41.9kDa (372aa) 40-57KDa (SDS-PAGE under reducing conditions) |
| Amino Acid Sequence | KAFPETRDYS QPTAAATVQD IKKPVQQPAK QAPHQTLAAR FMDGHITFQT AATVKIPTTT PATTKNTATT SPITYTLVTT QATPNNSHTA PPVTEVTVGP SLAPYSLPPT ITPPAHTTGT SSSTVSHTTG NTTQPSNQTT LPATLSIALH KSTTGQKPVQ PTHAPGTTAA AHNTTRTAAP ASTVPGPTLA PQPSSVKTGI YQVLNGSRLC IKAEMGIQLI VQDKESVFSP RRYFNIDPNA TQASGNCGTR KSNLLLNFQG GFVNLTFTKD EESYYISEVG AYLTVSDPET IYQGIKHAVV MFQTAVGHSF KCVSEQSLQL SAHLQVKTTD VQLQAFDFED DHFGNVDECS SDYTLEHHHH HH |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Concentration | 0.5mg/ml (determined by Absorbance at 280nm) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Salaun B., et al. (2004) Am J Pathol. 164:861-871. Kanao H., et al. (2005) Cancer Res. 65:8640-8645. |
| Background | LAMP3, also known as lysosome-associated membrane glycoprotein 3, is a member of the lysosome-associated membrane protein family. LAMP3 and CD68 share very similar predicted structure. It may play a role in dendritic cell function and in adaptive immunity. Overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces. Recombinant human LAMP3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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