| Product Name | LAR/PTPRF Antibody: HRP |
|---|---|
| Description | PTPRF or leukocyte common antigen-related protein (LAR) is a widely expressed protein tyrosine phosphatase with an extracellular receptor region that resembles a cell adhesion molecule. PTPRF removes phosphate group from β-catenin, an event that may subsequently facilitate cell-cell adhesion and ensure the stability of the cadherin complex. This phosphatase has also been implicated in various cellular processes such as neurite growth, nerve regeneration, actin remodeling and regulation of insulin function (1,2,3,4). Anti-PTPRF (C-terminal) antibody is specific for the extracellular and cytoplasmic subunits of human PTPRF (approx. 210, 150 and 85 kDa). Detection of the PTPRF bands by immunoblotting is specifically inhibited by the immunizing peptide. Mouse Anti-Human LAR/PTPRF Monoclonal IgG2a |
| Synonyms | FLJ43335 Antibody, FLJ45062 Antibody, FLJ45567 Antibody, LAR Antibody, LAR protein Antibody, LARFN5C Antibody, LARS Antibody, LCA homolog Antibody, Leukocyte antigen related (LAR) PTP receptor Antibody, Leukocyte antigen related Antibody, Leukocyte antige |
| Host | Mouse |
| Clone | S165-38 |
| Immunogen | Fusion protein amino acids 1315-1607 (cytoplasmic C-terminus) of human LAR. 97% identical in both rat and mouse. >80% identity with PTPRD and PTPRS. >50% identity with PTPRM and PTPRK. |
| Isotype | IgG2a |
| Specificity | Detects ~85kDa (full length protein is 210 kDa – smaller due to proteolysis into P-subunit containing transmembrane and intracellular domains. |
| Reactivity | Human, Mouse, Rat |
| Applications | ICC, IF, WB |
| Form | Purified, in PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
| Gene Id | NP_002831.2. 5792 |
| Uniprot | P10586 |
| Supplier | Stressmarq Biosciences |
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