| Product Name | LC3C Antibody: RPE |
|---|---|
| Description | Light chain 3 (LC3) is a microtubule-associated protein with an approximate molecular mass of 17kDa, and can be found ubiquitously throughout mammalian tissue. LC3 plays a role in autophagy; once the autophagic process is initiated in a cell, LC3 is conjugated to phosphatidylethanolamine to form LC3-II. This molecule is recruited to the autophagosome at the time of fusion with lysosomes, and LC3-II in autolysosomal lumen is degraded. Therefore, monitoring LC3 is an important tool for detecting autophagy and autophagy-related processes. LC3C is one of three isoforms which exhibits the lowest expression relative to the other two isoforms. Its highest expression is seen in placenta, lung and ovary. Mouse Anti-Human LC3C Monoclonal IgG1 |
| Synonyms | MAP1LC3C Antibody, ATG8J Antibody, Autophagy-related protein LC3 C Antibody, Autophagy-related ubiquitin-like modifier LC3 C Antibody, LC3 like protein 2 Antibody, MAP1 light chain 3 like protein 2 Antibody, MAP1 light chain 3 like protein 3 Antibody, MAP |
| Host | Mouse |
| Clone | VB2 |
| Immunogen | Peptide derived from C-terminal region of human LC3C protein |
| Isotype | IgG1 |
| Specificity | Specific for LC3C. Does not detect LC3A, LC3B, GABARAP, GABARAPL1 or GABARAPL2. |
| Reactivity | Human, Mouse, Rat |
| Applications | IP, WB |
| Form | 10 mM sodium phosphate, pH7.2, 150 mM NaCl, 0.02% sodium azide |
| Gene Id | NP_001004343.1. 440738 |
| Uniprot | Q9BXW4 |
| Supplier | Stressmarq Biosciences |
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