| Product Name | LINGO1 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to LINGO1 |
| Synonyms | FLJ14594 antibody; LERN 1 antibody; LERN1 antibody; Leucine rich repeat and Ig domain containing 1 antibody; Leucine rich repeat neuronal 6A antibody; Leucine rich repeat neuronal protein 1 antibody; Leucine rich repeat neuronal protein 6A antibody; Leucine-rich repeat and immunoglobilin domain-containing protein 1 antibody; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 antibody; Leucine-rich repeat neuronal protein 1 antibody; Leucine-rich repeat neuronal protein 6A antibody; LIGO1_HUMAN antibody; Lingo 1 antibody; LINGO1 antibody; LRR and Ig domain containing Nogo Receptor interating protein antibody; Lrrn 6a antibody; Lrrn6a antibody; Lrrn6a protein antibody; MGC17422 antibody; Nogo Receptor interacting protein antibody; PRO227 antibody; UNQ201 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant human Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 protein (42-240AA) |
| Isotype | IgG |
| Target | LINGO1 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC, WB |
| Form | Liquid |
| Diluent Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Uniprot | Q96FE5 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity). |
| Supplier | Cusabio |
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