| Product Name | LL 37 (human) biotinylated, pegylated |
|---|---|
| Description | LL 37 (human) biotinylated, pegylated is the N-terminally biotinylated version of the host defence peptide LL 37 with a biotin group attached via a pegylated chain, PEG(4). The presence of the biotin tag allows numerous biochemical and microbiological applications. LL 37, derived from the C-terminal of human cathelicidin antimicrobial peptide (CAMP, hCAP18), has antimicrobial, antitumour, antiviral and immunomodulatory properties and also has physiological functions in chemotaxis, promotion of wound closure, and angiogenesis. |
| Synonyms | AM-200, AM200, Biotin-[PEG(4)]-LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES-OH, LL 37 (human) biotinylated, LL-37, LL37, LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES, PEG(4), angiogenesis, antimicrobial, antitumour, antiviral, biotin, chemotaxis, immunomodulatory, pegylated chain, pegylated is the N-terminally biotinylated |
| Molecular Weight | 4967 Da |
| Target | Antibacterials |
| Amino Acid Sequence | Biotin-[PEG(4)]-LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES |
| Form | Freeze dried solid |
| Purity | >95% by HPLC |
| Storage | Store frozen, dessicated and in the dark |
| Notes | Modifications: Biotinylation and pegylation on the N terminus |
| References |
Kahlenberg and Kaplan (2013) Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease. J. Immunol. 191(10) 4895 PMID: 24185823Bandurska et al (2015) Unique features of human cathelicidin LL€37. BioFactors 41 289 PMID: 26434733Chen et al (2018) Roles and Mechanisms of Human Cathelicidin LL-37 in Cancer. Cell Physiol.Biochem. 47 1060 PMID: 29843147 Related areas All biotin labelled peptides >All antimicrobial peptides > |
| Supplier | Isca Biochemicals Limited |
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