| Product Name | LL 37 (human) scrambled |
|---|---|
| Description | LL 37, a 37 amino acid host defence peptide derived from the C-terminal of human cathelicidin antimicrobial peptide (CAMP, hCAP18), has antimicrobial, antitumour, antiviral and immunomodulatory properties and also has physiological functions in chemotaxis, promotion of wound closure, and angiogenesis. LL 37 (human) scrambled is the control peptide for LL-37 [AM-001]. |
| Synonyms | AM-002, AM002, GLKLRFEFSKIKGEFLKTPEVRFRDIKLKDNRISVQR, LL 37, LL 37 (human) scrambled, LL37, control , hCAP18), host defence peptide, human cathelicidin antimicrobial peptide (CAMP |
| Molecular Weight | 4493.3 Da |
| Target | Antibacterials |
| Amino Acid Sequence | GLKLRFEFSKIKGEFLKTPEVRFRDIKLKDNRISVQR |
| Form | Freeze dried solid |
| Purity | >95% by HPLC |
| Storage | Store dry, dark and frozen |
| Notes | Modifications: None |
| References | Kahlenberg and Kaplan (2013) Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease. J. Immunol. 191(10) 4895 https://doi.org/10.4049/jimmunol.1302005 Bandurska et al (2015) Unique features of human cathelicidin LL€37. BioFactors 41 289 doi:10.1002/biof.1225 Chen et al (2018) Roles and Mechanisms of Human Cathelicidin LL-37 in Cancer. Cell Physiol.Biochem. 47 1060 doi: 10.1159/000490183 |
| Supplier | Isca Biochemicals Limited |
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